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AFP Rabbit anti-Mouse, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 703094

Encompass

Catalog No. 70-309-4


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Description

Description

This antibody is predicted to react with Rat, Pig, Monkey. Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

AFP (Alpha-Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure the renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Specifications

Specifications

AFP
Recombinant Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
P02772
AFP
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11576
Western Blot
3H2L7
Unconjugated
Afp
Liquid
Afp
Protein corresponding to Mouse AFP [aa399-aa597]
Protein A
RUO
Antibody
Monoclonal
Mouse
SDS
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