Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Phenylpropanoids and polyketides
  6. Cinnamic acids and derivatives
  7. AG 490, Tocris Bioscience™

AG 490, Tocris Bioscience™

Catalog Number 041410
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
133550-30-8
C17H14N2O3
294.31
TUCIOBMMDDOEMM-RIYZIHGNSA-N
5328779
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
This item is not returnable. View return policy
133550-30-8
C17H14N2O3
294.31
TUCIOBMMDDOEMM-RIYZIHGNSA-N
5328779
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N

Description

EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor

Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vitro and tumor cell invasion in vivo.
Quantity 10 mg
Synonym tyrphostin b42, tyrphostin ag 490, e-n-benzyl-2-cyano-3-3,4-dihydroxyphenyl acrylamide, tyrphostin ag490, tyrphostin ag-490, alpha-cyano-3,4-dihydroxy-n-benzylcinnamide, 2e-n-benzyl-2-cyano-3-3,4-dihydroxyphenyl prop-2-enamide, ag-490 tyrphostin b42, n-benzyl-2-cyano-3-3,4-dihydroxyphenyl acrylamide, chembl56543
Formula Weight 294.31
Percent Purity >99%
Chemical Name or Material AG 490

Safety and Handling

Recommended Storage Store at Room Temperature
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit