Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Phenylpropanoids and polyketides
  6. Cinnamic acids and derivatives
  7. AG 494, Tocris Bioscience™

AG 494, Tocris Bioscience™

Catalog Number 061950
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
133550-35-3
C16H12N2O3
280.283
HKHOVJYOELRGMV-XYOKQWHBSA-N
tyrphostin b48, tyrphostin ag 494, tyrphostin ag-494, e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylacrylamide, alpha-cyano-3,4-dihydroxy-n-phenylcinnamide, chembl56731, 2e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylprop-2-enamide, e-2-cyano-3-3,4-dihydroxyphenyl-n-phenyl-2-propenamide, n-phenyl-3,4-dihydroxybenzylidenecyanoacetamide, tocris-0619
5328771
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
This item is not returnable. View return policy
133550-35-3
C16H12N2O3
280.283
HKHOVJYOELRGMV-XYOKQWHBSA-N
tyrphostin b48, tyrphostin ag 494, tyrphostin ag-494, e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylacrylamide, alpha-cyano-3,4-dihydroxy-n-phenylcinnamide, chembl56731, 2e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylprop-2-enamide, e-2-cyano-3-3,4-dihydroxyphenyl-n-phenyl-2-propenamide, n-phenyl-3,4-dihydroxybenzylidenecyanoacetamide, tocris-0619
5328771
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N

Description

Potent EGFR-kinase inhibitor

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively).
Quantity 50 mg
Formula Weight 280.28
Percent Purity >98%
Chemical Name or Material AG 494

Safety and Handling

Recommended Storage Desiccate at +4°C
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit