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AG 494, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
133550-35-3
C16H12N2O3
280.283
HKHOVJYOELRGMV-XYOKQWHBSA-N
tyrphostin b48,tyrphostin ag 494,tyrphostin ag-494,e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylacrylamide,alpha-cyano-3,4-dihydroxy-n-phenylcinnamide,chembl56731,2e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylprop-2-enamide,e-2-cyano-3-3,4-dihydroxyphenyl-n-phenyl-2-propenamide,n-phenyl-3,4-dihydroxybenzylidenecyanoacetamide,tocris-0619
5328771
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
This item is not returnable. View return policy
133550-35-3
C16H12N2O3
280.283
HKHOVJYOELRGMV-XYOKQWHBSA-N
tyrphostin b48,tyrphostin ag 494,tyrphostin ag-494,e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylacrylamide,alpha-cyano-3,4-dihydroxy-n-phenylcinnamide,chembl56731,2e-2-cyano-3-3,4-dihydroxyphenyl-n-phenylprop-2-enamide,e-2-cyano-3-3,4-dihydroxyphenyl-n-phenyl-2-propenamide,n-phenyl-3,4-dihydroxybenzylidenecyanoacetamide,tocris-0619
5328771
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N

Potent EGFR-kinase inhibitor

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.7 μM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC 50 values are 42, 6 and > 100 μM respectively).
Quantity 50mg
Formula Weight 280.28
Percent Purity >98%
Chemical Name or Material AG 494

Recommended Storage : Desiccate at +4°C