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AG 555, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
133550-34-2
C19H18N2O3
322.364
GSQOBTOAOGXIFL-WJDWOHSUSA-N
tyrphostin b46,z-2-cyano-3-3,4-dihydroxyphenyl-n-3-phenylpropyl prop-2-enamide,n-3 inverted exclamation marka-phenylpropyl-3,4-dihydroxybenzylidenecyanoacetamide
5353390
(Z)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
This item is not returnable. View return policy
133550-34-2
C19H18N2O3
322.364
GSQOBTOAOGXIFL-WJDWOHSUSA-N
tyrphostin b46,z-2-cyano-3-3,4-dihydroxyphenyl-n-3-phenylpropyl prop-2-enamide,n-3 inverted exclamation marka-phenylpropyl-3,4-dihydroxybenzylidenecyanoacetamide
5353390
(Z)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N

Potent EGFR-kinase inhibitor

Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Induce G1 growth arrest selectively in transformed cells (IC50 values are 6.4 and 9.4 μM in HPV16-immortalized and normal keratinocytes respectively).
Quantity 50mg
Formula Weight 322.36
Percent Purity >99%
Chemical Name or Material AG 555

Recommended Storage : Desiccate at +4°C