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  7. AG 99, Tocris Bioscience™

AG 99, Tocris Bioscience™

Catalog Number 049750
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
122520-85-8
C10H8N2O3
204.19
MFCD00133901
USOXQZNJFMKTKJ-XVNBXDOJSA-N
5328768
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
NC(=O)C(=C\C1=CC=C(O)C(O)=C1)\C#N
This item is not returnable. View return policy
122520-85-8
C10H8N2O3
204.19
MFCD00133901
USOXQZNJFMKTKJ-XVNBXDOJSA-N
5328768
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
NC(=O)C(=C\C1=CC=C(O)C(O)=C1)\C#N

Description

EGFR-kinase inhibitor

Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activation of caspase-like proteases in vitro.
Quantity 50 mg
Synonym tyrphostin 46, tyrphostin a46, tyrphostin b40, alpha-cyano-3,4-dihydroxy cinnamide, 3,4-dihydroxy-alpha-cyanocinnamamide, tyrphostin ag 99, e-2-cyano-3-3,4-dihydroxyphenyl prop-2-enamide, 2-propenamide, 2-cyano-3-3,4-dihydroxyphenyl, 2e-2-cyano-3-3,4-dihydroxyphenyl prop-2-enamide, tyrphostin ag99
Formula Weight 204.18
Percent Purity >99%
Chemical Name or Material AG 99

Safety and Handling

Recommended Storage Desiccate at +4°C
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