Invitrogen™ AGTR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3210

Catalog No. PA3210

Description

PA3-210 detects AGTR2 in human samples. PA3-210 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures. The PA3-210 immunogen is a synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2.

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Specifications

• Antigen: AGTR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Agtr2
• Gene Alias: AGTR2; AI316812; Angiotensin ii at2; angiotensin II receptor type 2; angiotensin II receptor, type 2; angiotensin II type 2 receptor; angiotensin II type-2 receptor; angiotensin receptor 2; AT>sub>2>/sub>R; AT2; AT2 receptor; AT2R; AT2-R; ATGR2; AW107640; MRX88; type-2 angiotensin II receptor
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.02% sodium azide
• Gene Accession No.: P50052
• Gene Symbols: Agtr2
• Immunogen: Synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2.
• Regulatory Status: RUO
• Gene ID (Entrez): 186
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid