Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
AHNAK Monoclonal Antibody (EM-09), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Thermo Scientific MA110050
SDSDocumentsProduct Certifications Promotions
DescriptionAHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predomitly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.
|AHNAKRS, MGC5395, AHNAK-related, desmoyokin, neuroblast differentiation-associated protein AHNAK|
|4° C, do not freeze|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot|
|Bacterially expressed fragment of N-terminal domain of human AHNAK1.|
Provide Content Correction
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok