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AHNAK Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 166371AP

Catalog No. 50-173-1075


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Description

Description

AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predomitly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.
Specifications

Specifications

AHNAK
0.6 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q09666
AHNAK, AHNAK nucleoprotein, AHNAKRS, Desmoyokin, PM227
Rabbit
IgG
150 μL
-20°C
Primary
79026
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
AHNAK
Liquid
AHNAK
AHNAK Fusion Protein Ag9986
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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