Tocris Bioscience™ AI-3 

ARE activator; induces Nrf2-ARE-dependent transcription

Catalog Number	Mfr. No.	Quantity
51-451-0	Tocris Bioscience™ 5145/10	10mg
51-455-0	Tocris Bioscience™ 5145/50	50mg

Description

Antioxidant response element (ARE) activator; disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Induces cytoprotective gene expression in vitro and in vivo.

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Specifications

• Product Type: AI-3
• Inhibitors: AI-3
• Molecular Weight: 292.8
• Purity: >98

For Research Use Only