Tocris Bioscience AI-3
ARE activator; induces Nrf2-ARE-dependent transcription
Manufacturer: Tocris Bioscience 5145/50
DescriptionAntioxidant response element (ARE) activator; disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Induces cytoprotective gene expression in vitro and in vivo.
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