AIB3 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 39836

Catalog No. 50-199-2892

Description

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Specifications

• Antigen: AIB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCOA6
• Gene Alias: Activating signal cointegrator 2; activating signal cointegrator-2; AIB3; Amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ASC2; ASC-2; Cancer-amplified transcriptional coactivator ASC-2; KIAA0181; mKIAA0181; NCOA6; Ncoa7; NRC; NRC RAP250; Nuclear receptor coactivator 6; Nuclear receptor coactivator RAP250; nuclear receptor-activating protein 250; Nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor interacting protein,PRIP; Peroxisome proliferator-activated receptor-interacting protein; PPAR interacting protein PRIP; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; Thyroid hormone receptor-binding protein; TRBP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23054, 56406
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: Lot-Specific
• Formulation: 70mM tris HCl with 1% BSA, 105mM NaCl, 30% glycerol, 70mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: Q14686, Q9JL19
• Gene Symbols: NCOA6
• Immunogen: This AIB3 antibody was raised against a recombinant protein corresponding to amino acids 22-146 of mouse AIB3.
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG