AIF-1/Iba1, Mouse anti-Human, DyLight 680, Clone: rAIF1/1909, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275760FR

Catalog No. NB008950

Description

AIF-1/Iba1 Monoclonal antibody specifically detects AIF-1/Iba1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: AIF-1/Iba1
• Clone: rAIF1/1909
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: AIF1
• Immunogen: AIF-1/Iba1 Antibody (rAIF1/1909) was developed against purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)
• Monoclonal or Polyclonal: Monoclonal
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Test Specificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

• Applications: Immunohistochemistry,Immunohistochemistry (Paraffin)
• Conjugate: DyLight 680
• Format: Purified,Conjugated
• Gene Alias: AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
• Host Species: Mouse
• Isotype: IgG1
• Primary or Secondary: Primary
• Quantity: 0.1 mL
• Research Discipline: Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
• Target Species: Human