Aiolos Monoclonal Antibody (8B2), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 39658

Catalog No. 50-199-2765

Description

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Specifications

• Antigen: Aiolos
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: O08900
• Gene Symbols: Ikzf3
• Immunogen: This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Western Blot
• Clone: 8B2
• Conjugate: Unconjugated
• Gene: Ikzf3
• Gene Alias: 5830411O07Rik; AIO; AIOLOS; BOS_19124; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); Ikaros family zinc finger protein 3; Ikzf3; LOC100356392; Zfpn1a3; zinc finger DNA binding protein Aiolos; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); ZNFN1A3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 22780
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid