Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

AIPL1 Mouse anti-Canine, Human, Rat, Clone: OTI2B11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503695

Catalog No. 50-167-4531


Add to cart

Description

Description

Aipl1 was initially identified as a protein implicated in Leber congenital amaurosis (LCA), an autosomal recessive disorder thought to be caused by the abnormal development of photoreceptors. Aipl1 is a tetratricopeptide repeat protein that is highly homologous to ARA9, a protein involved in the HSP90-mediated nuclear translocation and transactivation of the aryl hydrocarbon receptor. Aipl1 has also been found to function as part of a chaperone heterocomplex, interacting with Hsp90 and Hsp70. Aipl1 also associates with the cell cycle regulator NUB1. It is thought that Aipl1 cooperates with Hsp70 but not Hsp90 to suppress the formation of NUB1 inclusions, and these interactions are necessary in the normal photoreceptor maturation, as mutations that lead to LCA also compromise the interactions with the Hsp chaperones. At least three isoforms of Aipl1 are known to exist.
Specifications

Specifications

AIPL1
Monoclonal
0.73 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9JLG9, Q9NZN9
AIPL2, LCA4
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23746, 489447, 59110
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI2B11
Unconjugated
AIPL1
Liquid
AIPL1
Full length human recombit protein of human AIPL1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Rat
Documents
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit