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AKAP12 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550576

Catalog No. PA550576


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Description

Description

The antibody detects endogenous levels of total AKAP12 protein.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Specifications

Specifications

AKAP12
Polyclonal
Unconjugated
AKAP12
Liquid
AKAP12
Synthetic peptide corresponding to residues near the C terminal of human A kinase (PRKA) anchor protein 12
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1.2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q02952
SSeCKS, AKAP250
Rabbit
IgG
100 μL
-20°C
Primary
9590
Documents
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