AKAP12 Rabbit anti-Human, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 251991AP
DescriptionThe A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|A kinase anchor protein 12, AKAP 12, AKAP 250, AKAP12, AKAP250, Gravin, Myasthenia gravis autoantigen|
|Immunohistochemistry (Paraffin), Western Blot|
|AKAP12 Fusion Protein Ag17769|
|Antigen Affinity Chromatography|
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