AKAP12 Mouse anti-Human, Clone: OTI1B6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527420
DescriptionThe A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|AKAP250, SSeCKS, A-kinase anchor protein 12, A-kinase anchor protein, 250kDa, AKAP 250, Src-Suppressed C Kinase Substrate, kinase scaffold protein gravin, myasthenia gravis autoantigen gravin|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 266-557 of AKAP12 produced in E.coli|
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