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AKAP12 Mouse anti-Human, Clone: OTI1B6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527420

Catalog No. PIMA527420


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Description

Description

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Specifications

Specifications

AKAP12
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q02952
AKAP250, SSeCKS, A-kinase anchor protein 12, A-kinase anchor protein, 250kDa, AKAP 250, Src-Suppressed C Kinase Substrate, kinase scaffold protein gravin, myasthenia gravis autoantigen gravin
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9590
Immunohistochemistry (Paraffin), Western Blot
OTI1B6
Unconjugated
AKAP12
Liquid
AKAP12
Human recombit protein fragment corresponding to amino acids 266-557 of AKAP12 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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