AKT3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA588857

Catalog No. PIPA588857

Description

Immunogen sequence: EEREEWTEAI QAVADRLQRQ EEERMNCSPT SQIDNIGEEE MDASTTHHKR KTMNDFDYLK LL; Positive Samples: SH-SY5Y, 293T; Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.

Specifications

• Antigen: AKT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AKT3
• Gene Symbols: Akt3
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 93-154 of human AKT3
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.41 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q63484, Q9WUA6, Q9Y243
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10000, 23797, 29414
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid