Tocris AL 8697
Potent and selective p38alpha inhibitor
Manufacturer: Tocris 4753/10
DescriptionPotent and selective p38α inhibitor (IC50 = 6nM). Exhibits 14-fold greater inhibition of p38α compared to p38β; also displays 300-fold selectivity for p38α compared to a panel of 91 kinases. Exhibits anti-inflammatory properties.
- Chemical Name: N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide
- Formula: C21H21F3N4O
- CAS Number: 1057394-06-5
- Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
- Purity: >98
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