Tocris™ AL 8697

Potent and selective p38alpha inhibitor

Manufacturer: Tocris™ 4753/50

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Catalog No. 47-535-0

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For Research Use Only


    Inhibitors AL 8697
    Purity >98
    Molecular Weight 402.41
    Quantity 50mg
    Product Type AL 8697

    Potent and selective p38α inhibitor (IC50 = 6nM). Exhibits 14-fold greater inhibition of p38α compared to p38β; also displays 300-fold selectivity for p38α compared to a panel of 91 kinases. Exhibits anti-inflammatory properties.

    • Chemical Name: N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide
    • Formula: C21H21F3N4O
    • CAS Number: 1057394-06-5
    • Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
    • Purity: >98

  • Description & Specifications

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