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ALDH3A1 Mouse anti-Human, Clone: OTI1C6, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501139

Catalog No. 50-167-2280


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Description

Description

Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
Specifications

Specifications

ALDH3A1
Monoclonal
0.96 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P30838
ALDH3, ALDHIII
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
218
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI1C6
Unconjugated
ALDH3A1
Liquid
ALDH3A1
Full length human recombit protein of human ALDH3A1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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