ALDH3A1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 155781AP
DescriptionAldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P11883, P30838, P47739|
|Aldehyde dehydrogenase 3, ALDH3, ALDH3A1, ALDHIII|
|11670, 218, 25375|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|ALDH3A1 Fusion Protein Ag7977|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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