ALDH3A1 Mouse anti-Human, Clone: OTI1C6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525098
DescriptionAldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ALDH3A1; aldehyde dehydrogenase 3 family, memberA1; ALDH3; ALDHIII; MGC10406; aldehyde dehydrogenase 3A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; aldehyde dehydrogenase, dimeric NADP-preferring; stomach aldehyde dehydrogenase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of ALDH3A1 produced in HEK293T cell|
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