ALDH5A1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 173191AP
DescriptionAldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P51649, P51650, Q8BWF0|
|ALDH5A1, SSADH, SSDH|
|214579, 291133, 7915|
|Immunohistochemistry (Paraffin), Western Blot|
|ALDH5A1 Fusion Protein Ag11293|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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