BioVision Inc EZDetect Aldo-keto Reductase Activity Assay Kit (Colorimetric): EZDetect Aldo-keto Reductase Activity Assay Kit (Colorimetric): Simple and ultrasensitive method to measure Aldo Keto reductase activity in cells
Manufacturer: BioVision Inc K847100
EZDetect Aldo-keto Reductase Activity Assay Kit (Colorimetric): Aldo-keto Reductases (AKRs) are a superfamily of NAD(P)H linked oxidoreductases which contains more than 190 members. AKRs play roles in intermediary metabolism, biosynthesis and detoxification. Many studies demonstrate increasing expression of AKRs in cancers such as lung, liver and colon cancers. BioVision's EZDetect Aldo-keto Reductase Activity Assay Kit provides a convenient tool for sensitive detection of AKR activity in a variety of samples. In this assay, AKR acts on a general substrate and converts NADP+ to NADPH. This NADPH reacts with the AKR probe and generates color. This color is proportional to the activity of AKR in the sample. This kit can detect AKR activity as low as 0.001 mU in samples and has been validated with AKR1B10, AKR1C1 and AKR1C3. Further tests are in progress for other members of the AKR family. BioVision charges an Ice pack and Insulated Container fee of $25.00 for each order.
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