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Aldolase B Mouse anti-Human, Clone: OTI3E10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525545

Catalog No. PIMA525545


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Description

Description

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related  ft.housekeeping ft. genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Specifications

Specifications

Aldolase B
Monoclonal
1.00 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P05062
ALDB, ALDO2, aldolase 2, aldolase B, fructose-bisphosphatase, fructose-bisphosphate aldolase B, liver-type aldolase
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
229
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI3E10
Unconjugated
ALDOB
Liquid
ALDOB
Full length human recombit protein of ALDOB produced in HEK293 cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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