Tocris™ Aliskiren hemifumarate

Potent renin inhibitor; antihypertensive

Manufacturer: Tocris™ 5491/50

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Catalog No. 54-915-0

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For Research Use Only


    Specifications

    Description Aliskiren hemifumarate
    Molecular Weight 609.83
    Purity >99
    Quantity 50mg
    Product Type Aliskiren hemifumarate

    Potent renin inhibitor (IC50 = 0.6 and 80nM for human and rat respectively). Exhibits selectivity for renin over a range of other aspartic proteinases (>5000nM). Lowers blood pressure in a hypertensive rodent model. Orally active.

    • Chemical Name: (αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide hemifumarate
    • Formula: C30H53N3O6.1/2C4H4O4
    • CAS Number: 173334-58-2
    • Solubility: Soluble to 100mM in water and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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