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ALKBH3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549622

Catalog No. PA549622

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Predicted to react with bovine based on sequence homology.

Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
Specifications

Specifications

ALKBH3
Polyclonal
PBS with 0.09% sodium azide
Q96Q83, Q8K1E6
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, 11411-, Alkylated DNA repair protein alkB homolog 3, DEPC-1, Prostate cancer antigen 1, ALKBH3, ABH3, DEPC1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
221120, 69113
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ALKBH3
Liquid
ALKBH3
KLH conjugated synthetic peptide between 242-269 amino acids from the C-terminal region of human ALKBH3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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