Molecular Probes Alkyne, Succinimidyl Ester (3-Propargyloxypropanoic Acid, Succinimidyl Ester)
alkyne, succinimidyl ester (3-propargyloxypropanoic acid, succinimidyl ester)
Manufacturer: Molecular Probes A10279
DescriptionConjugates prepared with the amine-reactive alkyne, succinimidyl ester can be detected with an azide-containing molecule in a click chemistry reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls functional groups that are not unique click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.
|Alkyne, Succinimidyl Ester (3-Propargyloxypropanoic Acid, Succinimidyl Ester), 1mg, Yellow, Solid, 225.2 Molecular Weight, Alkyne Dye Type, C10H11NO5 Molecular Formula, Used For Labeling Chemistry|
|Cell analysis, labeling chemistry, labeling amines, amine-reactive fluorophores, click chemistries, cell proliferation with click chemistry|
|Alkyne, Succinimidyl Ester (3-Propargyloxypropanoic Acid, Succinimidyl Ester)|
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For Research Use Only. Not for use in diagnostic procedures.