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alpha-Smooth Muscle Actin Mouse anti-Human, Mouse, Rat, Several Species, Alexa Fluor™ 594, Clone: 1A4/asm-1, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233006AF594

Catalog No. NP23306A594


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Description

Description

alpha-Smooth Muscle Actin Monoclonal antibody specifically detects alpha-Smooth Muscle Actin in Human, Mouse, Rat, Porcine, Baboon, Bovine, Canine, Chicken, Feline, Guinea Pig, Goat, Monkey, Rabbit, Sheep samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

alpha-Smooth Muscle Actin
1A4/asm-1
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
Conjugated, Purified
ACTA2
N-Terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH
Protein A purified
Angiogenesis, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Extracellular Matrix, Loading Controls, Phospho Specific, Stem Cell Markers
Primary
59.0
Baboon, Bovine, Canine, Chicken, Feline, Goat, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 594
50 mM sodium borate with 0.05% sodium azide
AAT6, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, sma, smooth muscle actin
Mouse
IgG2a Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
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