ALX4 Mouse anti-Human, Clone: OTI1F2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526062
DescriptionThis gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal domit disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|FND2, aristaless-like homeobox 4, homeobox protein aristaless-like 4, homeodomain transcription factor ALX4|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of ALX4 produced in HEK293T cell|
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