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  7. AM 114, Tocris Bioscience™

AM 114, Tocris Bioscience™

Catalog Number 256450
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
856849-35-9
C20H21B2NO5
377.01
SRPIKXGUPAKTIZ-UHFFFAOYSA-N
3, 5-Bis-[benzylidene-4-boronic acid]-1-methylpiperidin-4-one
57369225
[4-[[5-[(4-boronophenyl)methylidene]-1-methyl-4-oxopiperidin-3-ylidene]methyl]phenyl]boronic acid
B(C1=CC=C(C=C1)C=C2CN(CC(=CC3=CC=C(C=C3)B(O)O)C2=O)C)(O)O
This item is not returnable. View return policy
856849-35-9
C20H21B2NO5
377.01
SRPIKXGUPAKTIZ-UHFFFAOYSA-N
3, 5-Bis-[benzylidene-4-boronic acid]-1-methylpiperidin-4-one
57369225
[4-[[5-[(4-boronophenyl)methylidene]-1-methyl-4-oxopiperidin-3-ylidene]methyl]phenyl]boronic acid
B(C1=CC=C(C=C1)C=C2CN(CC(=CC3=CC=C(C=C3)B(O)O)C2=O)C)(O)O

Description

20S proteasome inhibitor

Inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50 ∽ 1 μM). Displays anticancer activity; inhibits cell growth in human colon cancer HCT116 p53+/+ cells (IC50 = 1.49 μM).
Quantity 50 mg
Formula Weight 377.01
Percent Purity >97%
Chemical Name or Material AM 114

Safety and Handling

Recommended Storage Store at +4°C
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