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AM 580, Tocris Bioscience™

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Quantity:
10mg
50mg

Chemical Identifiers

102121-60-8
C22H25NO3
351.446
SZWKGOZKRMMLAJ-UHFFFAOYSA-N
4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid
2126
CHEBI:64210

Retinoic acid analog; RARα agonist

An analog of retinoic acid that acts as a selective RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFNγ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro.
Quantity 50mg
SMILES CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
IUPAC Name 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid
Formula Weight 351.44
Chemical Name or Material AM 580
Grade >98%

Recommended Storage : Store at Room Temperature