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Aminoacylase Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI2D3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525618

Catalog No. PIMA525618


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Description

Description

Aminoacylase is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. The aminoacylase gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in aminoacylase cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids.
Specifications

Specifications

Aminoacylase
Monoclonal
0.29 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q03154, Q6AYS7, Q99JW2
ACY-1, ACY1D, N-acyl-L-amino-acid amidohydrolase, acylase, aminoacylase-1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
109652, 300981, 476602, 95
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI2D3
Unconjugated
ACY1
Liquid
ACY1
Full length human recombit protein of ACY1 produced in HEK293 cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse, Rat
Documents
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