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AMOTL2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550322

Catalog No. PA550322


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Description

Description

The antibody detects endogenous levels of total AMOTL2 protein.

Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Specifications

Specifications

AMOTL2
Polyclonal
Unconjugated
AMOTL2
Liquid
AMOTL2
Fusion protein corresponding to residues near the C terminal of human angiomotin like 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.7 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9Y2J4
KIAA0989
Rabbit
IgG
100 μL
-20°C
Primary
51421
Documents
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