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AMPD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 197801AP

Catalog No. 50-173-2536


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Description

Description

The antibody is specific to AMPD1.

AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism. It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia. There are three functional isoforms of AMPD. AMPD1 (E.C. No 3.5.4.6. ) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. This protein is the predomit member of AMPD multi-gene family and is considered as the sensor of the cell ft.s changing energy requirements. AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid. Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.
Specifications

Specifications

AMPD1
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P10759, P23109, Q3V1D3
AMP deaminase 1, AMP deaminase isoform M, AMPD1, MAD, MADA, Myoadenylate deaminase
Rabbit
IgG
150 μL
-20°C
Primary
229665, 25028, 270
Western Blot
Unconjugated
AMPD1
Liquid
Ampd1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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