AMZ2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550330
The antibody detects endogenous levels of total AMZ2 protein.AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predomitly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phethroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
|Fusion protein corresponding to residues near the C terminal of human archaelysin family metallopeptidase 2|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
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