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Androgen R/NR3C4 Antibody (AR441 + DHTR/882), DyLight 650, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP247857C
Description
Androgen R/NR3C4 Monoclonal specifically detects Androgen R/NR3C4 in Human, Mouse (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
Androgen R/NR3C4 | |
Monoclonal | |
DyLight 650 | |
50mM Sodium Borate with 0.05% Sodium Azide | |
AR | |
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275) | |
0.1 mL | |
Primary | |
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues. | |
Store at 4C in the dark. | |
IgG1 κ |
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence | |
AR441 + DHTR/882 | |
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence | |
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy | |
Mouse | |
Protein A or G purified | |
Breast Cancer, Cancer, Cellular Markers, Phospho Specific | |
367 | |
Human, Mouse (Negative) | |
Purified |
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