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Androgen R/NR3C4 Mouse anti-Human, Mouse (Negative), Biotin, Clone: AR441 + DHTR/882, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP247857B

Catalog No. NBP47857B

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Androgen R/NR3C4 Monoclonal antibody specifically detects Androgen R/NR3C4 in Human, Mouse (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.


Androgen R/NR3C4
AR441 + DHTR/882
Immunohistochemistry, Immunohistochemistry-Paraffin
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR (AR441); Recombinant human DHTR protein (DHTR/882)
Protein A or G purified
Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Human, Mouse (Negative)
Immunohistochemistry, Immunohistochemistry (Paraffin)
PBS with 0.05% Sodium Azide
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
IgG1 Kappa/IgG1 Kappa
0.1 ml
Store at 4C in the dark.
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
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