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Androgen R/NR3C4 Mouse, Clone: AR441, Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2478540.2MG
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DescriptionAndrogen R/NR3C4 Monoclonal antibody specifically detects Antigen in Human, Mouse (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin).
|Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready|
|AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy|
|Breast Cancer, Cancer, Cellular Markers|
|Human, Mouse (Negative)|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF|
|PBS with No Preservative|
|A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR.|
|Protein A or G purified|
|Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
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