ANK2 Mouse anti-Human, Mouse, Clone: S105-17, Abnova™
Mouse monoclonal antibody raised against synthetic peptide of human ANK2.
Manufacturer: Abnova Corporation MAB12854
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq]
|Mouse monoclonal antibody raised against synthetic peptide of human ANK2.|
|In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot|
|Immunocytochemistry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to amino acids 203-496 of human ANK2.|
|Protein G purification|
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