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ANKMY2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550324

Catalog No. PA550324


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Description

Description

The antibody detects endogenous levels of total ANKMY2 protein.

ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell maligcies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Specifications

Specifications

ANKMY2
Polyclonal
Unconjugated
ANKMY2
Liquid
ANKMY2
Fusion protein corresponding to residues near the N terminal of human ankyrin repeat and MYND domain containing 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q8IV38
ZMYND20
Rabbit
IgG
100 μL
-20°C
Primary
57037
Documents
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