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ANKMY2 Mouse anti-Human, Clone: OTI1C12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526345

Catalog No. PIMA526345


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Description

Description

ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell maligcies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Specifications

Specifications

ANKMY2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8IV38
ZMYND20
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
57037
Immunohistochemistry (Paraffin), Western Blot
OTI1C12
Unconjugated
ANKMY2
Liquid
ANKMY2
Full length human recombit protein of ANKMY2 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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