Invitrogen™ Annexin A2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA186306

Catalog No. PIPA186306

Description

Predicted to react with bovine, mouse, pig and rat based on sequence homology. In Western blot, this antibody detects a band at ~35 kDa in A431 and A549 cell lysates. Goat anti Human Annexin II (N-Terminal) antibody recognizes an epitope within the N terminal (NT) region of Annexin II, a member of a family of structurally related calcium binding proteins implicated in mediating the the intracellular action of calcium.

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Annexin A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANXA2
• Gene Alias: 33-kDa calcimedin; 33-kDa lymphocyte Ca>2+>- binding protein; 33kDa lymphocyte Ca>2+>- binding protein; 36-kDa calelectrin; annexin 2; annexin A2; annexin A2 isoform 2; annexin II; Annexin-2; ANX2; ANX2L4; ANXA2; AW215814; CAL1H; calpactin I heavy chain; calpactin I heavy chain (p36); calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; Placental anticoagulant protein IV; protein I
• Host Species: Goat
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 302
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07355
• Gene Symbols: ANXA2
• Immunogen: Peptide sequence STVHEILCKLSLEGD corresponding to the N-terminal region of Annexin II (NP_001002858.1; NP_004030.1; NP_001002857.1).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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