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Invitrogen™ ANP32C Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5101062
Description
Antibody detects endogenous levels of total ANP32C.
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
Specifications
ANP32C | |
Polyclonal | |
Unconjugated | |
ANP32C | |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member C; acidic (leucine-rich) nuclear phosphoprotein 32 family, pseudogene; acidic leucine-rich nuclear phosphoprotein 32 family member C; acidic nuclear phosphoprotein 32 family member C; ANP32C; Anp32cl; Anp32c-ps; Anp32-ps; EG448829; Phosphoprotein 32-related protein 1; pp32 related 1; PP32R1; Tumorigenic protein pp32r1 | |
Rabbit | |
Affinity chromatography | |
RUO | |
23520 | |
-20°C | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
O43423 | |
ANP32C | |
A synthesized peptide derived from human ANP32C(Accession O43423), corresponding to amino acid residues N125-Y175. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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