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ANP32C Mouse anti-Human, Clone: OTI10A10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527188

Catalog No. PIMA527188


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Description

Description

ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
Specifications

Specifications

ANP32C
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O43423
Acidic leucine-rich nuclear phosphoprotein 32 family member C, Phosphoprotein 32-related protein 1, Tumorigenic protein pp32r1, PP32R1
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23520
Immunohistochemistry (Paraffin), Western Blot
OTI10A10
Unconjugated
ANP32C
Liquid
ANP32C
Full length human recombit protein of ANP32C produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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