ANT1/2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 159971AP
This antibody recognizes both of ANT1 and ANT2.Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintece of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P05141, P12235, P48962, P51881, Q05962, Q09073|
|AAC1, ADP,ATP carrier protein 1, ADP/ATP translocase 1, ANT, ANT 1, ANT1/2, PEO2, PEO3, SLC25A4, T1|
|11739, 11740, 25176, 291, 292, 85333|
|Immunoprecipitation, Western Blot|
|ANT1/2 Fusion Protein Ag7787|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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