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ANT1/2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 177961AP

Catalog No. 50-173-1796


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Description

Description

This antibody recognizes both of ANT1 and ANT2. The predicted molecular weight of ANT1/2 protein is around 32 kDa. While 60 kDa protein can also be observed, which has been proposed as the dimmer of ANT1/2.

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintece of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
Specifications

Specifications

ANT1/2
0.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05141, P12235, P48962, P51881, Q05962, Q09073
2F1, AAC2, ADP,ATP carrier protein 2, ADP/ATP translocase 2, ANT 2, ANT1/2, SLC25A5, T2, T3
Rabbit
IgG
150 μL
-20°C
Primary
11739, 11740, 25176, 291, 292, 85333
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SLC25A4
Liquid
SLC25A4, Slc25a5
ANT1/2 Fusion Protein Ag11956
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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