14-3-3 epsilon Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528937
PA5-28937 targets 14-3-3 epsilon in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples. The PA5-28937 immunogen is recombit fragment corresponding to a region within amino acids 1 and 255 of Human 14-3-3 epsilon. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 1 and 255 of Human 14-3-3 epsilon|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|PBS with 20% glycerol and 0.025% Proclin 300; pH 7|
|14-3-3E, KCIP-1, MDCR, MDS, 14-3-3 epsilon, 14-3-3 protein epsilon, mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1, tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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