MilliporeSigma anti-20S Proteasome alpha1, 2, 3, 5, 6, 7-Subunits Clone: MCP231,
Mouse Monoclonal Antibody
Manufacturer: MilliporeSigma ST1049100UL
Specifically detects 20S Proteasome α1, 2, 3, 5, 6, & 7-Subunits Clone: MCP231 in Human, Mouse, Rabbit, Rat, Yeast samples, and it is validated for ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immuno BlottingProteasomes are large multi-subunit complexes, that are localized in the nucleus and cytosol, and selectively degrade intracellular proteins. They play a major role in the degradation of many proteins involved in cellular processes such as cell cycling, apoptosis, and proliferation. The human proteasome contains two copies of each of seven different α-type and β-type subunits assembled to form a stack of four seven-membered rings. The α-subunits comprise the outer rings while the β-subunits comprise the inner rings. The α-subunits contain information for the binding of regulatory complexes such as PA700 and PA28.
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|20S Proteasome α1, 2, 3, 5, 6, & 7-Subunits|
|Recognizes α1, 2, 3, 5, 6 and 7 subunits of 20S proteasome in human placental proteasome preparations.|
|ELISA, Immuno Blotting, Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen)|
|Human, Murine, Rabbit, Rat, Yeast|
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